Fever and goose bumps are a symptom of chilliness and chills. Before the onset of fever, the sensation of chills and goose bumps occurs because the thermogenic agent acts on the thermoregulatory center, causing contraction of the skin vasculature and erector spinae muscles. Chills are caused by the contraction of skeletal muscles, resulting in increased heat production, while goose bumps are caused by the contraction of skin blood vessels, reducing heat dissipation. The increased heat production and decreased heat dissipation causes an increase in body temperature. Therefore goose bumps, or chills, are a precursor to fever, and the body temperature rises rapidly and peaks in a very short period of time. If accompanied by chills and shivering, it may be a sign of an infectious disease, including a bacterial infection, or a viral infection. It needs to be combined with other symptoms to find the site of infection, and sputum culture or blood culture can be done to find the type of bacteria and pathogens.