Membranous nephropathy proteinuria down time is related to the severity of the disease, can not be generalized, its proteinuria down time is generally in a few months to a year, two years, and even some patients proteinuria never decline. The clinical manifestation of membranous nephropathy is nephrotic syndrome, i.e., hypoproteinemia, high degree of edema, large amount of proteinuria, hyperlipidemia. A large amount of immune complex deposition can be seen on the epithelial side of glomerular capillary collaterals under electron microscope. Clinical treatment is generally symptomatic using glucocorticoids and immunosuppressants. Immunosuppressive therapy is usually indicated when large amounts of proteinuria are present, i.e., proteinuria > 3.5 g/day. Due to the disease characteristics of membranous nephropathy and individual differences, the effect of hormone and other immunosuppressant therapy varies. Therefore, the remission time of proteinuria usually ranges from several months to one or two years, and even in some cases, proteinuria can never be reduced. If you are diagnosed with membranous nephropathy, it is recommended to consult the doctor in time and take active treatment under the doctor’s guidance, do not take medication on your own to avoid delaying your condition.