There are many causes of headache, rheumatic headache may be due to lupus encephalopathy, secondary infection, cerebral edema, hypertension and other causes, in addition to the use of anti-inflammatory painkillers such as ibuprofen and other symptomatic treatment and the use of anti-rheumatic drugs for rheumatism, such as methotrexate and other therapies, it is also necessary to target the treatment according to the specific cause of the disease. Clinical commonly used non-steroidal anti-inflammatory drugs to relieve headache symptoms, you can take ibuprofen, acetaminophen and other anti-inflammatory analgesic drugs. In addition, rheumatic diseases mainly include rheumatoid arthritis, systemic lupus erythematosus, etc., but also need to carry out anti-rheumatic treatment, clinically commonly used anti-rheumatic drugs, including LiuZiSulphonpyridine, leflunomide, azathioprine, methotrexate, and so on. Due to individual differences, there is no absolute safest and most effective drugs, adverse reactions such as dizziness, diarrhea and other timely medical treatment, drug allergy is prohibited. Of course, rheumatic headache may also be caused by other reasons, such as lupus encephalopathy, cerebral edema, hypertension, etc., you need to be in the regular hospital to clarify the specific causes of headache, in order to target the treatment. Therefore, rheumatic headache patients are advised to consult a regular hospital in a timely manner, under the guidance of the doctor’s diagnosis and treatment, and follow the doctor’s instructions to use drugs, do not self-medication.