Why do medications start out effective and end up ineffective?

At the beginning of the medicine is effective, and finally no effect, may be because the human body on the drug resistance, may also be the aggravation of the disease caused by the original drug is ineffective for the disease, but also due to the influence of blind obedience to the psychological.
The human body produces drug resistance, usually due to the pathogen that causes the disease to reduce the sensitivity of the drug or even disappear, resulting in the loss of the original effect of the drug.
The original drug, its efficacy is mainly for the original condition to treat, aggravation of the condition or other pathological changes in the body, may lead to the original drug on the current condition of the therapeutic effect is weakened.
Blindly follow the psychological refers to people tend to follow the trend of blindly using drugs, in the psychological effect of the initial feel effective, but due to the inability to truly targeted treatment, over time, will find that the disease in fact did not relieve.
When the use of drugs for a period of time, found that the drug has no effect, should promptly go to the hospital to consult the doctor, and carefully follow the doctor’s advice to use drugs, do not blindly use drugs, so as not to delay the course of the disease.