Low mean platelet distribution width indicates that the size and volume of platelets in the body do not vary much and are relatively uniform.
Platelet mean distribution width is one of the indicators for clinical observation of platelets, which can reflect the dispersion of platelet volume size in peripheral blood, often expressed by its coefficient of variation, with a normal reference range of 9% to 17%. The normal reference range is 9% to 17%. Below 9% indicates a low level, and above 17% indicates a high level.
Aplastic anemia, malignant tumors and other bone marrow suppression after radiotherapy and chemotherapy leads to hematopoietic hypoplasia, when the platelet distribution width is low. Higher platelet distribution width is commonly found in peripheral blood where platelets are over-destroyed and the bone marrow has good hematopoietic function, such as erythrocytic anemia, immune thrombocytopenia, and so on.
If it is high, it means that the platelets in the body are of different sizes and their volume is not average. If it is low, it means that the size and volume of platelets in the body are more uniform. If the distribution width is simply low and the platelet count is not abnormal, there is not much clinical significance.