Knee soreness cannot be relieved quickly, it takes some time. Physiotherapy and medication can be given according to the etiology of vascular compression, soft tissue injury, rheumatoid arthritis and so on. 1. Vascular compression: prolonged squatting may lead to slow blood flow in the knee area, resulting in insufficient blood supply to the nerves and slow metabolism of the surrounding tissues, thus leading to knee pain. At this time, you can lift the squatting posture, give the appropriate massage, hot compresses and so on can relieve the knee acid. 2. Soft tissue injury: long-term large-scale running, hiking, climbing stairs and other sports, can lead to soft tissue injury, thus causing knee soreness, you can use hot towels and other hot compresses on the knees, if the symptoms of knee soreness is more serious, you can apply the diclofenac diethylamine emulsion and other drugs external. 3. Rheumatoid arthritis: rheumatoid arthritis is a systemic autoimmune disease, the pathogenesis of which is still unclear, can make the soft tissue of the knee joints have been destroyed, resulting in knee soreness, pain and other symptoms. It can be treated with methotrexate, glucocorticoids, ibuprofen and other drugs. There may be other reasons for knee pain, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment. All of the above drugs should be applied under the guidance of a physician, and should not be used without authorization.