Leukemia platelet drop quickly leads to bleeding in all parts of the body, which can be relieved by general treatment, medication, chemotherapy, radiotherapy, surgery and platelet-raising therapy. 1. General treatment: take more rest, minimize outdoor activities to prevent infection from occurring. Nutritional supplements, high protein, high calorie, easy to digest food such as milk, eggs and so on. 2. Drug therapy: patients with chronic granulocytic leukemia can be treated with tyrosine kinase inhibitors such as imatinib and dasatinib. 3. Chemotherapy: Commonly used chemotherapeutic drugs such as vincristine and Zorubicin can rapidly remove a large number of leukemia cells from the patient’s body and relieve the symptoms. 4. Radiotherapy: When the effect of chemotherapy is unsatisfactory, we can consider combining with radiotherapy to relieve the symptoms. 5. Surgery: hematopoietic stem cell transplantation is the only possible cure. 6. Platelet-boosting therapy: drugs such as thrombopoietin can be given as appropriate to promote the recovery of platelet index. Once leukemia patients are diagnosed, they should receive standardized treatment under doctor’s guidance as soon as possible, closely observe the changes of their condition and undergo regular review.