Metformin is usually taken with or immediately after a meal. Metformin is a blood sugar-lowering medication. It can be used to treat people with type 2 diabetes who are not well controlled with diet and exercise alone. Metformin can be used either alone or in combination with a sulfonylurea or insulin. Common adverse reactions to metformin are gastrointestinal reactions such as nausea, abdominal pain, and bloating; therefore, it is usually taken with or immediately after meals. Diabetes with ketoacidosis, hepatic and renal insufficiency, heart failure, major surgical procedures, hypoxia, and hypersensitivity to the product are contraindicated. If you need to use the drug, you need to use it under the guidance of a doctor, do not use the drug on your own to avoid adverse effects on the body.