Patients with advanced stage of liver cancer will have symptoms of liver odor. Liver odor is due to liver function damage and failure, the ability of liver cells to remove thiol-like substances is reduced, so that such substances are discharged through respiratory and urinary tracts, and can be smelled in the exhaled gas or discharged urine of patients similar to the smell of garlic or rotten apples. It is mostly seen in patients with liver cancer, liver cirrhosis, hepatic encephalopathy and other liver failure. Patients with advanced liver cancer will not only have the symptom of liver odor, but also have itchy skin, which are caused by the accumulation of toxins in the liver. Using enema therapy or antibiotic treatment to promote the detoxification and metabolism ability of the liver can reduce the symptom of liver odor. Patients with advanced stage of liver cancer will have symptoms of liver odor, which often suggests that the condition is critical, and it is recommended to consult doctor in time and carry out targeted treatment or therapy under doctor’s guidance.