Long-term application of Povidon suppositories has certain side effects, such as disturbance of the vaginal environment, local dryness, burning sensation and discomfort in the vulva, so Povidon suppositories should not be applied for a long time. The main ingredients are curcuma oil and ice chips, which are safe Chinese medicine ingredients, but long-term application can cause a series of symptoms. Because the drug contains ice chips, some patients may feel cold and chilly inside the body after using it, and even experience chills and allergies. Long-term use can lead to disturbance of the vaginal environment, which can aggravate vaginitis or cause recurrent vaginitis that does not heal. Mild side effects can be removed by stopping the medication, washing the vulva and vaginal examination, while more serious allergic reactions must be treated symptomatically in a hospital.