Enlarged blackheads on men’s face may be related to increased androgen secretion, exuberant sebaceous gland secretion, and abnormal keratinization of hair follicle openings. Clinical solutions include general treatment, medication, and acid peels. 1. Increased secretion of androgens: Increased secretion of androgens can lead to thickening of pores and growth of blackheads. It is generally recommended to wash your face with lukewarm water, keep your face clean, prohibit spicy and stimulating, greasy food, and eat more fresh vegetables and fruits. 2. Excessive sebaceous gland secretion, abnormal follicle opening keratinization: because of staying up late, eating spicy stimulation, do not pay attention to the skin clean and so on, resulting in the secretion of excessive oil, follicle opening keratinization abnormality will easily lead to hair follicle clogging, inflammation, blackheads and thickening of the pores. You can use topical medication as prescribed by your doctor, such as applying Vitamin A cream or Adapalene gel on your skin to dissolve the keratin. There are numerous causes of enlarged pores and blackheads on the face, and usually there is no improvement after corresponding treatments, it is recommended to go to the hospital in time for examination and treatment.