Andafen, generically known as recombinant human interferon a2b suppository, is usually recommended to be administered intravaginally at night before bedtime. Recombinant human interferon a2b suppositories are usually recommended to be used at night before going to bed, which reduces the possibility of activity and helps to promote the absorption as well as utilization of the drug by the body. Recombinant human interferon a2b suppository is a gynecological topical medication that needs to be applied with clean hands and gloves before use, in the vagina near the posterior cervical vault. If the patient has excessive leukorrhea, you need to use the drug to douche the vagina first, so as to avoid the presence of a large amount of leukorrhea, which may affect the therapeutic efficacy of the drug. In addition, regular review for 3 months is required. Adverse reactions of recombinant human interferon a2b suppository include increased leukorrhea, transient low-grade fever, and vaginal tingling, etc. It is contraindicated for those who are allergic to recombinant human interferon a2b suppository. In addition, the application of recombinant human interferon a2b suppositories carries certain risks of use, and it is recommended that patients use them under the guidance of a specialist.