The treatments for thyroid nodules with hyperthyroidism include medication, iodine radiation therapy and surgery, etc. Consult your doctor for specific treatments. 1. Medication: Thyroid nodules with hyperthyroidism need to be treated with drugs such as methimazole, propylthiouracil, propranolol and so on as prescribed by the doctor. 2. Iodine radiation therapy: Iodine radiation therapy destroys thyroid tissue and reduces the release of thyroid hormones, which in turn treats hyperthyroidism. 3. Surgery: Surgery can be considered for patients with thyroid nodules and hyperthyroidism if the nodules are large enough to cause pressure symptoms, such as difficulty in breathing or swallowing, or if long-term medication is ineffective or recurs after stopping medication. Patients diagnosed with thyroid nodules with hyperthyroidism are recommended to be treated under the guidance of a doctor.