Sildenafil can generally be taken together with anti-inflammatory drugs, but it is recommended that the interval of about half an hour, specific should follow the doctor’s instructions. Sildenafil is a drug for erectile dysfunction, and anti-inflammatory drugs usually refer to antibiotic drugs, such as roxithromycin, cephalosporin and so on. It has not been found that sildenafil and anti-inflammatory drugs used together can cause serious adverse reactions. Therefore, it is generally believed that they can be taken together. However, there are also no studies on the safety of combined medications, so it is recommended to take them about half an hour apart. When applying sildenafil, it is important to note that the drug should not be taken with nitrates to avoid serious adverse reactions. Common adverse reactions to sildenafil include headache, flushing, dizziness, nasal congestion, indigestion, and visual abnormalities. When taking sildenafil and anti-inflammatory drugs together, you need to be under the supervision of a doctor.