With the correct use of intravenous drugs and proper handling, there is usually no harm in administering IVs. However, if the medication and operation are not standardized, IV drip may have hazards such as irritation of blood vessels, anaphylactic shock, respiratory distress, and in serious cases, it may be life-threatening. IV, also known as intravenous infusion, is a method of using the principle of atmospheric pressure and hydrostatic pressure of liquid to input liquid directly into the body through the vein. Since the medication goes directly into the blood vessels, it can cause some irritation and, in the case of more potent medications, may also cause a tingling sensation. When administering IV fluids, some drugs are subject to allergy testing, such as penicillins, cephalosporins, streptomycin and other drugs. If the patient is allergic to the infused drug, there will be symptoms of itching and edema of the skin, and in severe cases, anaphylactic shock will occur, which can be life-threatening if not treated in time. In addition, intravenous infusion may cause acute pulmonary edema and symptoms of respiratory distress if the infusion rate is too fast. If a large amount of air enters the vein, it will cause air embolism, and if not treated in time there will be severe hypoxia, which is life-threatening. Therefore, you must pay attention to the infusion of fluids, if there are symptoms of discomfort promptly notify the medical staff for treatment.