Aspirin and metoprolol can be taken together in the treatment of circulatory diseases, but need to be guided by professional doctors. 1. Aspirin is a non-steroidal anti-inflammatory drug that can inhibit platelet aggregation by acetylating platelet cyclooxygenase. The drug can prevent thrombosis. Metoprolol belongs to the β-adrenergic receptor blocking drugs, with negative variable force and negative variable time effects, can slow down the heart rate, inhibit cardiac contractility, delay atrial conduction and so on. 2. Aspirin is used to prevent thrombosis in myocardial infarction and atrial fibrillation, and can also be used to treat unstable angina. Metoprolol can be used to treat hypertension, angina pectoris, myocardial infarction, hypertrophic cardiomyopathy and many other diseases. 3. Some users of aspirin may experience adverse reactions such as nausea, vomiting, epigastric discomfort, and aspirin asthma. Common adverse reactions to Metoprolol include fatigue, headache, dizziness, bradycardia, etc. 4. Aspirin is contraindicated: it is contraindicated in those who are allergic to the drug, in the presence of severe heart failure or active peptic ulcer. Metoprolol is contraindicated in those who are allergic to the drug, have bradycardia or low blood pressure. These two drugs can be used together in the treatment of circulatory disorders, the instructions for the drug do not show any significant interactions, and it is recommended to use the drug in accordance with the doctor’s instructions.