Parkinson’s disease is a chronic disease that jeopardizes human health, this year, the prevalence of middle-aged and elderly people and young people have increased, the form is serious, but the specific manifestations of Parkinson’s disease are varied, and some symptoms are generally difficult to cause people to pay attention to, especially middle-aged and elderly people, the rate of timely diagnosis is low. What are the symptoms of Parkinson’s disease? 1, slow movement: this symptom is difficult for middle-aged and elderly people to associate with Parkinson’s disease, but if you find that wearing clothes, buttons, shoelaces, etc., the movement is significantly slower than in the past, you should be alert to Parkinson’s disease. 2, smell loss or loss: research found that 70% to 90% of the patients with Parkinson’s disease have smell loss symptoms, mainly manifested as olfactory discrimination, olfactory identification and olfactory threshold abnormalities, and found that smell loss is often in the tremor, slow movement and other motor symptoms before the emergence of the 3-7 years has been manifested, is currently being emphasized in the Parkinson’s disease early warning signals, but smell loss is also manifested in other diseases, so need to be identified. The first step is to identify the symptoms of Parkinson’s disease, so we need to do a good job of identification. 3, anxiety, depression mental disorder: Parkinson’s disease is often accompanied by symptoms, because of the impact of the disease on the patient’s psyche, but also found that may be earlier than the tremor, bradykinesia before the symptoms appeared. 4, hand and foot trembling: usually develops from the distal end of one side of the limb, such as the thumb and forefinger rubbing pill-like movements. Parkinson’s disease patients with trembling characterized by stationary trembling, if the patient’s hand quietly hanging down or placed on the table, legs, trembling obvious, holding something or sleep is disappeared, sitting down, leg trembling, this is the early trembling, trembling aggravated in the middle and late stages, the serious trembling affect sleep. 5, walking a leg dragging the ground, one arm does not throw the arm 6, mask face: the patient’s face is expressionless, joy, anger, sadness and happiness can not mobilize the facial muscles, can not be shown. 7, writing smaller and smaller, commonly known as “small writing syndrome”. 8, muscle stiffness: early from the unilateral limbs, patients feel muscle tightness or joint stiffness, inflexible activities, can occur in the proximal end of the limb (such as the neck, shoulders, hips) or the distal end (such as the ankle, wrist), often can cause pain. Therefore, clinically, there are many first stiffness type patients, early because of pain and consultation to orthopedics, pain department, also often misdiagnosed as cervical spondylosis, lumbar spondylosis, arthritis and other treatment. 9, ape posture: Parkinson’s disease patients affected by muscle ankylosis, trunk, limbs and knee joints will show a flexed posture, similar to the ape look. 10, walking body leaning forward, braking, panic gait 11, starting difficulties, small steps forward, turn around difficulties 12, sit down and stand up difficulties, unstable balance, easy to fall 13, sleep disorders: daytime drowsiness, insomnia at night, easy to wake up, nightmares and accompanied by punching and kicking and other action behaviors. 14, intractable constipation: may be before the appearance of Parkinson’s disease motor symptoms, Parkinson’s disease and anti-Parkinson’s disease drugs and will aggravate constipation. 15, bladder disorder: manifested as frequent urination and urgency. 16, greasy face, salivation, dysphagia, dysphonia, low voice, often in the later stages of the disease. 17, Accompanying dementia (not all)