Bone metastases occur in liver cancer, which is already in the advanced stage of cancer, and after treatment, a five-year survival rate of about 5% can be obtained, and the specific life expectancy can vary. Liver cancer is a common malignant tumor of digestive system caused by hepatitis virus, heredity, alcohol and other factors. With the development of tumor, distant metastasis, such as bone metastasis, will often occur in the late stage of liver cancer, and bone pain, pathological fracture and other clinical manifestations will usually occur at this time. Due to the complexity of the disease and poor physical condition of patients, non-surgical treatments such as radiotherapy, chemotherapy and targeted drug therapy are often used. After active treatment, the five-year survival rate of patients with liver cancer bone metastasis is about 5%. Patients should consult the doctor in time, complete relevant examination, make clear diagnosis and adopt corresponding treatment plan.