Patients with hepatitis who develop yellow eyes are most often considered to have jaundice. The most likely cause of jaundice is hepatocellular jaundice, which is caused by necrosis of liver cells due to viral hepatitis. If the bilirubin is above 34.2umol/L and the indirect bilirubin is mainly elevated, the patient is considered to have hepatocellular necrosis due to viral hepatitis. Patients need to have further blood tests for hepatitis B DNA or hepatitis C RNA to see if the virus is replicating. If the virus is replicating, combined with elevated glutathione and glutamic oxalacetic aminotransferase in liver function, further antiviral treatment should be actively considered. Oral medications and interferon injections can be considered for active treatment. In addition, patients need to be given liver-protective therapy, such as the use of reduced glutathione, diammonium glycyrrhizate and other drugs to actively treat.