Ultrasound does not confirm the diagnosis of lymphoma; it can only detect enlarged lymph nodes and masses. Lymphoma is a malignant tumor caused by malignant clonal proliferation of lymphocytes originating from lymphoid organs or lymphoid tissues. On clinical examination, the main features are painless and progressive lymph node enlargement, and some patients may present with fever. During ultrasound examination, the size, shape, structure and morphology of lymph nodes, as well as the surrounding tissues will be seen, which has certain reference value for the diagnosis of lymphoma, but the diagnosis of lymphoma cannot be confirmed directly by ultrasound examination. To confirm the diagnosis of lymphoma, it is necessary to do pathological section, and pathological diagnosis is the important basis for confirming the diagnosis of lymphoma. Therefore, ultrasound alone cannot confirm the diagnosis of lymphoma, and it needs to be combined with various imaging tests and pathological diagnosis for comprehensive analysis to confirm the diagnosis. For patients who are suspected of having lymphoma, they should pay attention to it and are recommended to go to the hospital as soon as possible for early detection, diagnosis and treatment under the guidance of physicians.