The best recovery methods for purpura include general therapy, glucocorticoids, immunosuppressants, splenectomy, and plasma exchange. Purpura consists of three types and the treatment varies.
1. Allergic purpura
(1) General treatment: bed rest in acute stage, fasting in case of gastrointestinal bleeding.
(2) Antihistamines: such as cimetidine and loratadine.
(3) Drugs to improve vascular permeability: e.g. vitamin C, carbachol etc.
(4) Glucocorticoids: mainly used for people with joint swelling and pain, acute progressive nephritis or nephrotic syndrome.
(5) Others: when the above treatments are not effective, immunosuppressants, such as cyclosporine and azathioprine, can be used.
2. Primary immune thrombocytopenia: ITP.
(1) General treatment: when platelets <20*10^9, should be strictly bedridden, avoid trauma.
(2) Glucocorticoid: it is the preferred treatment.
(3) Intravenous infusion of gammaglobulin: use with caution in diabetes mellitus and renal insufficiency.
(4) Thrombopoietic drugs: fast-acting, well-tolerated, mild side effects.
(5) Rituximab: it can remove B lymphocytes in the body and reduce the production of anti-platelet antibodies.
(6) Splenectomy: it is suitable for those who are ineffective in glucocorticoid treatment for 4-6 weeks and the disease has been prolonged for more than 6 months.
3. Thrombotic thrombocytopenic purpura.
(1) Plasma exchange and transfusion of fresh frozen plasma: as the treatment of choice.
(2) Others: glucocorticoids, high-dose intravenous immunoglobulin, cyclosporine, etc. may be effective.
Patients should not self-medicate, but should consult the doctor in time and use the medication under the doctor’s guidance.