There is no best way to relieve a headache from a cold, it can be relieved by medication and general supportive treatment for colds. Colds are often called acute upper respiratory tract infections, colds and headaches are mostly related to fever, to symptomatic treatment. Commonly used medications are antipyretic and analgesic drugs, such as acetaminophen and ibuprofen, which can relieve the symptoms of headache and fever. Meanwhile, the general supportive treatment for colds includes paying attention to strengthening nursing care, resting more and ensuring enough sleep. In the diet to light diet, drink more water, ensure adequate water intake. Pay attention to keep warm, avoid catching cold, overwork and so on. If the headache of cold and flu is severe and persists without relief, we need to be alert to the possibility of viral encephalitis. At the same time, cold symptoms accompanied by headache can also be seen in non-cold diseases, such as acute sinusitis. Therefore, if you have a cold headache that does not go away, or if you have a severe headache when you have a cold, you need to consult a doctor, complete the relevant examinations, and follow the doctor’s instructions for treatment.