Excessive H. pylori indicates the presence of an infection. For patients with penicillin allergy, other antibiotics can be taken for application, such as erythromycin and clarithromycin. For the treatment of Helicobacter pylori infection, the current main four-combination of drugs, i.e., proton pump inhibitors + bismuth + two antibiotics combined application, such as omeprazole + bismuth pectin + amoxicillin + metronidazole combination of drugs. This treatment plan requires two different antibiotics, if the patient is allergic to penicillin, other types of antibiotics can be applied under the guidance of the doctor for treatment, such as erythromycin, clarithromycin, furazolidone and so on. If medication is needed, it needs to be used under the direction of a doctor and the treatment should be carried out according to the doctor’s instructions.