After the occurrence of bacterial infections in children, antibiotics can be taken for treatment, and the drugs should be used in strict accordance with the doctor’s instructions. Clinically used penicillins include amoxicillin, cefaclor, ceftriaxone, roxithromycin, clarithromycin and so on, which can be used for children’s bacterial infectious diseases, and the corresponding preparation can be selected according to the cause of the disease. Due to individual differences, the drug does not exist the absolute most effective and safest, need to be under the guidance of the doctor combined with specific conditions to choose the most suitable for the child’s medication, the emergence of abdominal pain, dizziness, nausea and other adverse reactions recommended timely consultation, drug allergy is prohibited. Children’s bacterial infection after actively cooperate with the doctor to receive standardized drug treatment, can effectively control the inflammation, improve the prognosis of the disease. All of the above medications should be used under the guidance of a doctor, avoid self-medication.