Generally speaking, the erosion between anus and vagina of women is usually caused by vaginitis, perianal eczema, anal fistula and other diseases, which need to be treated by drugs and surgery according to the specific situation. 1. vaginitis: usually manifested as local burning pain, itching, even erosion after scratching, can be treated by medication under the guidance of a doctor, such as topical application of metronidazole cream, clindamycin ointment and other topical antibacterial cream, or oral metronidazole, tinidazole and other medications. 2. perianal eczema: perianal eczema is usually abnormal itching, often due to excessive scratching caused by vesicles, redness and swelling, etc., can be used under the guidance of a doctor, such as benadryl, paracetamol and other antihistamines, or local topical tacrolimus and pimecrolimus and other ointments for treatment. 3. anal fistula: often manifested as perianal next to repeated rupture pus, itching, the patient can be under the guidance of the doctor oral antibiotics to control inflammation, such as cefixime, ciprofloxacin and other drugs, or under the guidance of the doctor to carry out surgical treatment, such as anal fistulas excision, incision and hanging line surgery, and so on. It is recommended that patients go to the hospital in time to identify the cause of the disease and then targeted treatment. Daily attention should be paid to the anal and vaginal area of cleanliness and hygiene, change underwear, avoid spicy and stimulating food, to prevent the symptoms from worsening.