Creatinine 180μmol/L maintenance time can be individual differences depending on the cause of elevation, treatment effect, etc., and cannot be generalized. Creatinine is the blood creatinine, and its normal value is 53~106μmol/L for men and 44~97μmol/L for women, which is often used to determine whether the renal function is normal or not. The causes of elevated creatinine include physiologic and pathologic causes. Physiological causes such as strenuous exercise, excessive consumption of meat, mental stress, etc. may lead to elevated creatinine, which will gradually return to normal after the triggering factors are eliminated and will not last for a long time. Pathological causes such as drugs or acute glomerulonephritis lead to creatinine increase, through stopping drugs, standardized treatment, usually creatinine will drop and return to normal level. If the creatinine is 180μmol/L due to chronic kidney disease, it can be maintained for several months to several years with proper treatment, but if the disease progresses, it can’t be maintained for a long time, and there are differences between individuals due to the treatment effect, so it can’t be generalized. Therefore, if the examination found creatinine 180μmol / L, it is recommended to actively cooperate with the doctor to formulate a reasonable treatment plan, as soon as possible to control the condition, the blood creatinine indicators down to the normal range. During the treatment period, patients should pay attention to dietary control, maintain a low-salt, low-fat diet, do not eat too greasy or pickled food, and run and exercise appropriately, which will help the recovery of blood creatinine level.