Acne is mainly related to sex hormone levels, sebaceous gland secretion, proliferation of Propionibacterium acnes, abnormal keratinization of sebaceous gland ducts in hair follicles, and inflammation. In terms of endocrine factors, androgens play an important role in the development of acne. From the perspective of abnormal follicular sebaceous gland duct keratinization, if the follicular sebaceous gland ducts are over-keratinized, the caliber of the ducts becomes smaller, narrower, or obstructed, the normal discharge of sebum will be affected and acne will be formed. Infections from facial microorganisms may also cause inflammation with papules, pustules, nodules, and abscesses. Diets such as fats, sugars, and cocoa can increase sebum production. Irritating foods, such as chili peppers, strong alcohol, and fried foods, can aggravate the lesions. Mental factors such as overwork and emotional stress can also aggravate the condition. The occurrence of facial acne is related to many factors, you need to go to the hospital for a systematic examination, and then choose the appropriate treatment drugs.