The drugs for myelosuppression include chemotherapeutic drugs, targeted therapeutic drugs and antibacterial drugs. Due to individual differences in the situation, the specific circumstances of specific treatment, there is no myelosuppressive best medicine, only suitable for their own condition of the drug is the best. 1. Chemotherapy drugs (1) Alkylating agents: alkylating agents can interfere with DNA replication, broader anti-tumor spectrum and short half-life. They mainly include cyclophosphamide tablets, simustine capsules, isocyclophosphamide for injection, nimustine hydrochloride for injection and so on. (2) Demethylation drugs: mainly act on DNA methylation transferase, capable of causing DNA demethylation. It mainly includes decitabine for injection, azacitidine for injection, etc. (3) Plant-based chemotherapeutic drugs: plant-based chemotherapeutic drugs have fewer side effects than other chemotherapeutic drugs, but they can also produce cytotoxicity, including paclitaxel injection, docetaxel injection, high trichothecenes injection and so on. 2. Targeted therapeutic agents: imatinib mesylate tablets, nilotinib capsules, bortezomib for injection, etc. The above drugs will lead to a decrease in white blood cells, platelets and hemoglobin, and have myelosuppressive toxicity. 3. Antibacterial drugs: antibacterial drugs such as chloramphenicol injection, amphotericin B for injection, etc., have more obvious myelosuppressive effect, and the onset of the disease is more insidious, which can lead to impaired hematopoietic function of the bone marrow and reduce the number of megakaryocytes in the bone marrow. Specific conditions should be specifically analyzed, under the guidance of the doctor to choose the most appropriate treatment plan, do not self-medication to avoid adverse reactions.