A painful pimple inside the nose may be caused by excessive secretion of skin oil; it may also be the hair follicles are infected by pathogens, forming boils; in addition, nasal vestibular cysts can also cause pain. 1. Excessive skin oil secretion: If the patient’s endocrine disorders or dietary inattention, like to eat spicy and stimulating food will lead to excessive secretion of local skin oil, clogging the pores caused by the nose inside the pimple is very painful. 2. Hair follicle infection: when the hair follicles of the nasal skin are infected by pathogens, bacteria grow in the hair follicles, which will cause the hair follicles to be blocked, and then lead to the formation of acne. The skin inside the nose is more closely connected to the subcutaneous tissue, and once a pimple grows, the tension will be very high, stimulating the local receptors to cause pain. 3. Nasal vestibular cysts: Nasal vestibular cysts are often manifested as diffuse elevations inside the nasal cavity against the outside, often requiring surgical removal. A pimple in the nose is very painful, it is recommended to consult a doctor in a timely manner, a clear diagnosis, and follow the doctor’s instructions for treatment.