Hand, foot and mouth disease is an infectious disease caused by enterovirus, which mostly occurs in children under 5 years old and can cause herpes on the hands, feet and mouth. Individual children with severe disease can die if their disease progresses rapidly. There are more than 20 types of enteroviruses that cause HFMD. Coxsackievirus types 16, 4, 5, 9, and 10 of group A, types 2 and 5 of group B, and enterovirus type EV 71 are the more common pathogens of HFMD, among which coxsackievirus type A16 (Cox A16) and enterovirus type 71 (EV 71) are the most common. Transmission route: mainly through the gastrointestinal tract (fecal-oral route), but also through the inhalation tract (droplets, coughing, sneezing, etc.), and can be spread by contact with the patient’s oral and nasal secretions, skin or mucosal herpes fluid and contaminated hands and objects. The high incidence of HFMD occurs from May to July each year. Children often present with small rice-grain or mung bean-sized grayish-white herpes or red papules around the cheeks, tongue, soft palate, hard palate, inner lips of the mouth, heart of the hands and feet, elbows, knees, and buttocks of the child. The rash is not like a mosquito bite, a drug rash, a herpes on the lips and gums, or chicken pox, and is not itchy, painful, crusty, or scarred. In a few cases, especially in EV71-infected children, meningitis, encephalitis, cerebral cremasteritis, neurogenic pulmonary edema, circulatory disorders, etc. can occur, and the condition can be dangerous, resulting in death or sequelae. Preventive and control measures: 1. Children living in the diaspora (1) children should wash their hands with soap or hand sanitizer before meals and after going home; caregivers should wash their hands before touching children, changing diapers for children, and after handling feces; (2) infants’ diapers should be washed, exposed to the sun or disinfected in a timely manner; attention should be paid to maintaining the hygiene of the home environment, and the living room should be ventilated frequently and clothes should be dried regularly; (3) infants’ bottles, pacifiers and children’s (4) Children should not be taken to public places with poor air circulation during the epidemic; avoid contact with sick children; (5) Children with fever, rash and other related symptoms should go to medical institutions promptly; (6) Children treated at home should avoid contact with other children to reduce cross-infection. Parents should promptly dry or disinfect the affected child’s clothes and disinfect the child’s feces in a timely manner. (2) If there are serious or fatal cases, or if there are 2 or more cases in the same classroom within 1 week, it is recommended that the classroom where the case is located be suspended for 10 days; if there are a total of 10 or more cases in 1 week or if there are 2 or more cases in each of the 3 classes, it is recommended that the classroom where the case is located be suspended for 10 days; if there are a total of 10 or more cases in 1 week or if there are 2 or more cases in each of the 3 classes, it is recommended that the classroom where the case is located be suspended for 10 days; if there are 2 or more cases in each of the 3 classes, it is recommended that the classroom where the case is located be suspended for 10 days. (3) Educate and guide children to develop good hygiene habits such as proper hand washing; teachers should maintain good personal hygiene; (4) Maintain good ventilation in classrooms, dormitories and other places; regularly wash and disinfect toys, children’s personal hygiene utensils (water cups, towels, etc.), tableware and other items; (5) Regularly clean and disinfect activity rooms, bedrooms (6) Child care institutions should clean and disinfect toilets daily, and staff should wear gloves and wash their hands immediately after work; (7) Child care institutions should cooperate with the health department to take measures to prevent and control hand, foot and mouth disease. If the disease has developed, children with mild illness should be given an easily digestible diet and adequate hydration during home observation and treatment. Itchy skin can be treated with a topical stove glycolic lotion. Oral ulcers can be treated with chrysin ointment or 2% lidocaine topically. In addition, decoction of Chinese herbs such as Xia Gu Cao, Ban Lan Gen, Jin Yin Hua or Licorice can also have good effect.