It is understood that hand, foot and mouth disease is an acute infectious disease caused by the enterovirus, the city has cases throughout the year, including April-July and September-November for the high incidence of children aged 5 years and younger as the main susceptible population, especially the highest incidence of children aged 3 years and younger, adults generally do not appear symptoms after infection, but can spread the virus, so adults also It is necessary to do a good job of prevention a protection, to avoid the infection to infants and children. According to reports, the main source of infection for the sick baby and virus carriers, these two types of people droplets and feces contain a large number of viruses, viruses can be hosted in the hands, hand towels, toys, clothing, beds, quilts, tableware, bottles and other places, the baby is easy through contact with the affected child or the affected child’s personal belongings, inhalation of virus-contaminated air or contact with virus-contaminated items and be infected. At the beginning of the illness, the child will have a low fever, cough, runny nose, abdominal pain and other symptoms that are not obvious. After 1-2 days of fever and abdominal pain, pea-sized blisters or herpes will appear in the mucous membrane of the baby’s mouth, and small, round or oval papules will appear on the extremities, and in some cases, on the buttocks. Older babies will tell their mothers that their mouths hurt, while younger babies will show increased drooling, refusal to eat, poor appetite, and crying. Although most of the disease heals well, a few patients are more seriously ill and can be complicated by encephalitis, meningitis, myocarditis and pneumonia, which can be life-threatening if left untreated. Parents can identify HFMD through some simple methods once their child has a similar condition. The most typical symptom of HFMD is moderate fever (temperature around 38℃), followed by sore throat, young children show drooling and refusal to eat. When the child is not feeling well, parents should feel the child’s forehead and body more often to see if the fever is up, and check the mouth to see if there are multiple herpes on the mucous membrane of the throat, and whether there are papules or herpes around the distal parts of the hands and feet and the anus. The papules or herpes are usually the size of rice grains or green beans, round or oval in shape, surrounded by a red halo, and without obvious itching. Prevention is the key in the face of a multi-prevalent disease. During HFMD epidemic, you should take your baby to less crowded public places to reduce the chance of being infected; wash your hands regularly, especially before meals, after pooping and after going out to avoid mutual transmission of the virus; keep the living room clean and ventilated; wash and disinfect your baby’s utensils and toys frequently; provide your baby with adequate nutrition and ensure sufficient sleep to enhance the immunity of the body. Timely vaccination against hand, foot and mouth disease EV71. Most cases of serious illness or death from hand, foot and mouth disease are caused by EV71 virus infection, and EV71 vaccination can effectively reduce the occurrence of serious illness and death. Vaccination is recommended for children aged 6 months to 5 years old, and it is recommended to complete the entire immunization process by 12 months of age.