Many people do not know much about the transmission of hand, foot and mouth disease, such diseases are generally easy to suffer from children, so parents also need to pay attention to the spread of such diseases, the speed is also very fast, so in daily life, the child’s diet is to be reasonable, especially to enhance the child’s physical fitness, so as to avoid children suffering from such diseases, will not cause harm to health. The specific ways of transmission of hand, foot and mouth disease, there are many aspects, the following detailed introduction, so that more people have some knowledge of such diseases, so that in life, also know how to avoid the best. The way of transmission: the disease is transmitted in various ways, mainly through close contact with the crowd. The virus can be transmitted through saliva, herpes fluid, feces and other contaminated hands, towels, handkerchiefs, dental cups, toys, eating utensils, milk utensils, as well as bedding, underwear and other indirect contact; the virus in the patient’s throat secretions and saliva can be transmitted through droplets; such as contact with water contaminated by the virus, can also be infected by water; outpatient cross-infection and oral apparatus disinfection failure is also one of the reasons for transmission. Susceptible population: The population is generally susceptible to the enterovirus that causes HFMD, and immunity can be acquired after infection. Because of the lack of cross-protective power of antibodies after infection with different pathogens, the population can be repeatedly infected with the disease and most adults have acquired the corresponding antibodies through recessive infection, therefore, patients with HFMD are mainly preschool children, especially the highest incidence in the ≤3-year-old age group. According to foreign literature, the epidemic can occur once every 2-3 years in the population. Epidemic mode: HFMD is extremely widespread and not strictly regional. The disease can occur in all seasons, with summer and autumn being the most common and winter being the least common. The disease often occurs scattered after an epidemic outbreak, and kindergartens and nurseries are prone to collective infection during the disease epidemic. Families also have clusters of this disease. Cross-infection in hospital outpatient clinics and lax sterilization of oral instruments can also cause transmission. The disease is highly contagious, with complex transmission routes, high epidemic intensity and rapid spread, and can cause pandemics in a short period of time. Through the above introduction, the transmission of hand, foot and mouth disease are also have some understanding, this kind of disease in the early stage of treatment, and will not unduly endanger the child’s health, but delayed without treatment, will make the disease develop rapidly, in the treatment or on the child’s body, the treatment is very troublesome.