There are many different kinds of rashes, such as maculopapular rash, pemphigus, blistering rash, etc. Pediatricians often easily identify different causes based on the time of appearance, morphological distribution characteristics, and accompanying clinical manifestations of the rash. There are also common rash diseases in babies “hand, foot and mouth disease”. 1, clinical features Hand, foot and mouth disease occurs mostly in children under 5 years old, highly contagious, can be outbreaks of epidemic or distribution, summer epidemic. Initially low fever, small herpes on the oral mucosa, and then break down to form ulcers, painful to eat, the child’s appetite is reduced. Mostly maculopapular rash appears simultaneously on the skin of hands and feet, occasionally on the trunk, thighs and buttocks. The maculopapular rash quickly turns into a small herpetic rash. Sometimes it can be accompanied by aseptic meningitis, myocarditis, etc. 2, home care Give your child plenty of water, eat soft meals, avoid acidic drinks and harder foods, rinse your mouth with salt water to reduce oral pain. Do not scratch the rash to prevent secondary infection. Take oral antiviral drugs under the guidance of the doctor. Carefully observe the changes in your baby’s condition and seek medical attention as soon as you find that your child is not in good spirits or looks bad. Avoid contact with other children during the illness. 3.Prognosis Herpes hand and foot is self-limiting, usually after 3 to 4 d of the onset of the disease will naturally subside, do not leave scabs, oral ulcers gradually healed a few weeks after the onset of the disease, will not leave sequelae. Immunity to homozygous viral hand, foot and mouth disease can be acquired after the disease, but not for life. Most of the critically ill cases recover normal cardiopulmonary and cerebral functions and are completely cured after active resuscitation, but a few may leave sequelae, especially in patients with severe neurological involvement, and some children die due to cardiopulmonary failure, severe encephalitis, pulmonary hemorrhage or other complications.