Vulvar cancer has different treatment modes with different stages, and the effect of treatment is also different. Early stage of the disease can be treated by surgery, and the prognosis is relatively good, and some of them can reach the effect of clinical cure. If lymph node metastasis occurs in the middle stage, it can be treated with radiotherapy after surgery. When the disease has reached the advanced stage, it can be treated with bio-immunotherapy, which can prolong the patient’s life. Vulvar cancer is a malignant tumor of the female genital tract, and the cause of its development is still unclear. Considerations related to increasing age, persistent human papillomavirus infection, weakened immunity, cigarette smoking, chronic non-tumorigenic cutaneous mucosal lesions, and a history of precancerous vulvar lesions may exacerbate the risk of vulvar cancer. Vulvar cancer is a malignant tumor, and the mainstay of treatment is surgery. For example, in the early stage of vulvar cancer, the tumor is not too big, and the tumor can be completely removed through surgery. The prognosis of vulvar cancer patients with early surgical treatment is relatively good, and the survival rate of patients in 5 years can reach 90%, and some patients can achieve the effect of clinical cure. In mid-stage vulvar cancer with lymph node metastasis, radiotherapy is needed after surgery, but it is easy to recur, and the 5-year survival rate may be about 50%~70%. For advanced vulvar cancer, in addition to surgery and radiotherapy, it can also be combined with bioimmunotherapy, which can improve the quality of survival and can prolong the life of patients.