The size of adrenal hyperplasia surgery can not be generalized, surgery is divided into traditional surgery and minimally invasive surgery, at present, the general use of minimally invasive surgery, surgical trauma is small, no obvious discomfort symptoms, minimally invasive surgery belongs to the small surgery. Adrenal hyperplasia, which is caused by the extensive proliferation of chromophobe cells in the medulla, adrenal hyperplasia current treatment is still mainly based on surgery. Medication is also an option. Surgery is to remove most of the hyperplasia bilateral adrenal glands, not completely, so as not to affect the adrenal cortex function. For medication, commonly used drugs include adrenal receptor blockers, such as ketoconazole and mephedrone; neuromodulatory drugs including bromocriptine and rosiglitazone; and glucocorticoid receptor antagonists, such as mifepristone. According to the doctor’s advice to choose the right treatment for you, discomfort, timely consultation, so as not to miss the disease.