Waking up in the morning with sneezing and runny nose is usually due to cold air irritation, allergic rhinitis, vasomotor rhinitis, etc. Cold air irritation can be improved through nursing care, and allergic rhinitis and vasomotor rhinitis can be treated with medication under the guidance of a doctor. 1. Cold air irritation: usually it may be caused by the patient inhaling cold air in the morning, which will cause the patient to get up in the morning with sneezing and runny nose all the time, should drink more hot water and strengthen the exercise to improve their own resistance to alleviate such symptoms. 2. Allergic rhinitis: dust mites and pollen in the air when getting up are more, which is easy to stimulate the nasal mucosa to appear allergic rhinitis, resulting in sneezing, the patient can take loratadine, cetirizine and other medicines under the guidance of the doctor, which can alleviate the patient’s symptoms of nasal congestion and sneezing, and is prohibited for those who are allergic to the medicines. 3. Vasomotor rhinitis: vasomotor rhinitis is mainly due to the high sensitivity of blood vessels to hot and cold air, changes in temperature when getting up will stimulate vasoconstriction or diastole of the nasal mucosa, resulting in sneezing symptoms, the patient can be nasal spray mometasone furoate nasal spray, budesonide nasal spray and other medications for treatment, drug allergy is prohibited. It is recommended that patients actively go to the hospital for examination, after a clear diagnosis, follow the doctor’s instructions to standardize the use of drugs and treatment.