To determine the severity of hypertensive nephropathy, it is necessary to improve the urine routine, urine protein quantification, renal function tests and blood pressure monitoring, etc. Based on the patient’s glomerular filtration rate and combining with the clinical situation, the doctor will make professional analysis and comprehensive assessment to make a diagnosis on the severity of the disease. In the early stage of hypertensive nephropathy, the condition is not serious, with increase of trace protein in urine, accompanied by increase of nocturia, but the renal function is normal. When hypertensive nephropathy develops to the advanced stage, the condition is often more serious, with abnormal renal function manifestations, such as increased creatinine, which can lead to renal failure or even uremia in severe cases. Once found hypertensive nephropathy, it is recommended to cooperate with professional doctors for antihypertensive treatment as soon as possible, such as ACEI or ARB drugs, to control the blood pressure, to avoid developing to the seriousness of renal failure or uremia.