The site of pain in patients with duodenal ulcers is located mainly in the upper abdomen. Duodenal ulcers are most common in young adults, most of them occur in the bulbous part, and the site of pain is mainly located in the upper abdomen. However, the pain area of duodenal ulcers is not absolute, such as the posterior bulbous ulcers occurring in the descending and horizontal segments of the duodenum, the pain can radiate to the right epigastrium and back. Another example is giant ulcers often occur in the posterior wall, and the pain may radiate to the back. Rhythmic epigastric pain associated with meals, hunger pain, or night pain that is relieved by eating is most often seen in duodenal ulcers. It is recommended to go to the hospital in time when the above symptoms occur, to clarify the cause of the disease as soon as possible under the guidance of a professional physician, and to carry out regular treatment, so as to avoid delaying the condition.