The pain in the front side of the calf may be caused by local soft tissue inflammation, osteomyelitis, bone tumor, bone fracture, etc. It is recommended to take physical, medication and surgical treatment after further examination. 1. Inflammation: In general, pain in the front side of the calf bone is often considered to be caused by strain, trauma, fatigue and other soft tissue inflammation as well as tibial osteomyelitis, osteomyelitis, etc., which can be reduced activities, pay attention to rest, and use anti-inflammatory pain relieving plasters and creams, as well as oral anti-inflammatory pain relieving drugs such as Celecoxib, and penicillin and other antibiotics, if necessary. 2. Bone tumor: if further CT examination makes it clear that it is caused by bone tumor, then according to the stage of the tumor and the specific lesion, we need to adopt comprehensive treatment such as surgical resection and internal fixation, local radiation therapy, cyclophosphamide and other systemic chemotherapeutic drugs. 3. Fracture: If there is a fracture in the imaging examination, it is recommended to take manipulation, external fixation and other treatments according to the degree and type of fracture, and if necessary, surgical excision and internal fixation treatment. Therefore, it is recommended to go to the hospital in time for further CT and other examinations, and carry out appropriate treatment under the guidance of the doctor.