Sleeping at night, dry mouth and throat, should be clear cause of the cause of treatment, such as laryngitis, need to give anti-infection treatment; diabetes, need to give glucose-lowering treatment; gastroesophageal reflux esophagitis, need to give anti-inflammatory acid suppression and other treatments. 1. pharyngolaryngitis caused by dry throat, throat foreign body sensation and dry cough, in the treatment of the main target to give anti-inflammatory, antiviral drug therapy, such as amoxicillin capsules, roxithromycin capsules anti-inflammatory treatment, ribavirin tablets antiviral treatment and so on. 2. Diabetes mellitus is a common endocrine system diseases, in the clinic will also be manifested as dry mouth, but at the same time may also be accompanied by polyuria, polydipsia and other manifestations, given to the treatment of hypoglycemic drugs can improve the symptoms of dry mouth, dry throat, such as metformin tablets, gliclazide tablets. 3. Chronic gastritis, gastric reflux esophagitis and other digestive diseases caused by dry mouth, in the treatment of the main acid-based, such as omeprazole enteric-coated capsules, pantoprazole tablets and so on. For the persistence of sleep dry mouth and dry throat phenomenon, must promptly consult the doctor, and under the guidance of the doctor for standardized treatment.