It is abnormal to have the heart on the right side, but patients with right-sided hearts can be seen in clinical practice, which is associated with congenital developmental abnormalities. The normal heart is on the left side. The human heart is located in the lower left side of the middle of the chest cavity and is the size of each person’s fist. The heart is the power organ, providing circulation of blood. The heart consists of four chambers, including the left atrium, the left ventricle, the right atrium and the right ventricle. The heart is usually on the left side. For patients with right-sided heart, the symptoms of chest pain on the right side can appear in patients with coronary heart disease. The presence of chest pain on the right side needs to be clarified with the presence of right-sided heart condition, and it is recommended to give electrocardiogram, cardiac ultrasound, chest imaging, and coronary artery imaging to further clarify the condition.