Liuwei Di Huang Pill and methylcobalamin (tablets) are generally not recommended to be taken at the same time, if there is a therapeutic need can be under the guidance of the doctor for a period of time apart before taking. Six-flavored Dihuang Pill is composed of ripened rhubarb, cornelian cherry, moutan skin, Chinese yam, poria, zedoary, etc. It has the effect of nourishing yin and tonifying the kidneys, and is commonly used in the treatment of dizziness and tinnitus, lumbar and knee soreness and weakness (a feeling of soreness and weakness of the waist and knees), and bone vaporization and tidal fever (a burst of heat, feeling that the heat is penetrating from the inside of the bone outward), etc. The adverse effects and contraindications of taking Six-flavored Dihuang Pill are clearly defined. The adverse reactions and contraindications of taking Liuwei Di Huang Wan are not clear at the moment. Methylcobalamin tablets are indicated for the treatment of peripheral neuropathy and may cause adverse reactions such as rash, loss of appetite, nausea, vomiting, diarrhea, etc. It is contraindicated in patients with a history of hypersensitivity to methylcobalamin or any of the excipients in the prescription. It is generally not recommended to take the two at the same time, if you need to take at the same time should be based on the individual’s body and the recovery of the condition of a period of time before taking, it is recommended that the use of drugs under the guidance of a doctor.