A vague pain on the fifth day of wisdom tooth extraction may be caused by local infection and dry socket, and patients can get relief from the pain through general treatment, medication, and surgical treatment. 1. General treatment: patients after tooth extraction due to food debris attached to the wound, may cause pain, patients should pay attention to oral hygiene, brush teeth on time, rinse after eating, to a light diet, avoid spicy, stimulating food, you can use 3% hydrogen peroxide and saline on the affected area for rinsing alternately, to alleviate the symptoms of pain. 2. Medication: For patients with pain caused by wisdom teeth removal, pain medication such as ibuprofen, acetaminophen, etc. and antibiotics such as cefuroxime, metronidazole, ornidazole, etc. can be taken under the guidance of the doctor to prevent and control the inflammation of the affected area. 3. Surgery: For patients who have dry socket formation after wisdom teeth extraction, causing pain, they can go to the dentistry department of regular hospitals in time to perform debridement of the extraction wound to alleviate the symptoms. It is recommended that patients strictly follow the doctor’s instructions for medication, actively cooperate with the doctor’s treatment, pay attention to personal hygiene and oral care in life, and at the same time do a good job of monitoring the condition, if there is any abnormality in a timely manner to seek medical attention.