Recently, the number of children with HFMD has increased again. How can we prevent HFMD? Today we will talk about what is HFMD? What are the clinical manifestations of HFMD? How does HFMD spread? We hope that the content of the mission can help parents protect their babies from or reduce the risk of HFMD. Hand, foot and mouth disease is an acute infectious disease caused by enterovirus infection, mostly occurs in children under 5 years old, and the high incidence of hand, foot and mouth disease is from March to September every year. The main clinical manifestations include fever, mouth pain, anorexia, and scattered herpes or ulcers on the mucous membrane of the enclosure. The hands, feet, buttocks, arms and legs appear maculopapular rash, which later turns into herpes, and there may be inflammatory redness around the herpes and less fluid inside the herpes. Some cases present only as a rash or herpetic pharyngitis. Mild cases usually heal spontaneously in 5 to 7 days. Severe cases can be combined with fatal complications such as encephalitis, encephalomyelitis, neurogenic pulmonary edema, heart damage, etc. The condition is dangerous and the death rate is high. Therefore, HFMD requires early detection, early diagnosis and early treatment, and the majority of children have a good prognosis, while a few may be left with neurological sequelae. The source of HFMD infection is the patient and the latent infected person. Transmission routes: 1. digestive tract: fecal bite transmission; 2. respiratory tract: droplet transmission; 3. close or intimate contact with patients and their playthings, clothing, water sources, etc. The population is generally susceptible, but most of the patients are preschool children, especially infants and children under 3 years old. Immunity is generally acquired after infection, but not lifelong immunity. Because HFMD can be caused by a variety of enterovirus infections. It can develop in all seasons, with an incubation period of 2 to 7 days and an isolation period of 2 weeks. If a child has got HFMD, parents should carefully observe the child’s condition and take the child to the hospital as soon as the following manifestations appear 1. The body temperature is persistently higher than 39 degrees, and conventional fever reduction is not effective. 2.The child has poor mental health, drowsiness, vomiting, easily startled, shaking limbs, weakness, unstable standing and other neurological manifestations. 3.Abnormal increase or decrease of heart rate and breathing or irregular rhythm. 4.Flowering of the skin, chilling of the limbs, and cold sweating. The above manifestations are the early manifestations of severe cases. Particular attention should be paid to children under 3 years of age with onset of illness within 5 days. Timely detection of early manifestations of severe cases is crucial to reduce the mortality rate of HFMD. If a child develops symptoms such as fever and rash, he or she should be promptly seen at the hospital, while changes in condition should be closely observed and hospitalized as soon as the early manifestations of severe cases of HFMD mentioned above appear. Children with HFMD should not go to kindergartens and public places, avoid contact with other children and play, and take home isolation. Children’s pacifiers, bottles, dishes, towels and other items can be disinfected by boiling for 3 minutes; toys, tables and chairs can be disinfected with chlorine-containing disinfectants, such as 84 disinfectant or bleach, and cleaned daily according to the instructions; children’s sputum and feces are best poured into the appropriate amount of disinfectant, stirred and disinfected before pouring into the side house. Caregivers should wash their hands before touching the child, after changing diapers or after handling the child’s feces and stool. The key to preventing hand, foot and mouth disease is to pay attention to personal, family and environmental hygiene. It is very important to wash hands with soap or hand sanitizer before meals, after defecation and after going out; not to drink raw water or eat cold food; to ventilate the room frequently; and to dry clothes and blankets. Do not take children to public places with crowded and poor air circulation during epidemics, and avoid contact with sick children. Check your child’s skin and mouth every day during the epidemic period for any abnormalities, and pay attention to changes in the child’s body temperature. With a better understanding of HFMD, I believe that parents have realized that HFMD is preventable and treatable. As long as we mobilize all our strengths, we can definitely do a good job in preventing and controlling HFMD.