How to remove a thorn in the hand needs to be determined on a case-by-case basis. If you can’t pick it out on your own, you need to seek medical attention. 1. After sticking a thorn in the hand, observe it under the light, if you can see the end of the thorn, you can pick it out at home with a needle or use tweezers to clip it out. After the thorn is picked out, wash it with water and then disinfect it with iodine to prevent the wound from getting infected. 2. If you can see the end of the thorn, but can not be picked out, you can use transparent adhesive tape on the wound, and then tear it off, often able to bring out the thorn. 3. If the above methods are ineffective, or can not see the end of the thorn, and the pain is obvious, then you need to go to the hospital dermatology or general surgery, the doctor after observation, to determine the part of the thorn into the, try to pick out; otherwise you need to surgical incision to take out. After picking out the splinter, the patient needs to disinfect the wound regularly and protect the wound with band-aid to avoid infection, and can take antibiotics such as amoxicillin and cefaclor for treatment. It is also recommended to inject tetanus antitoxin to prevent tetanus.