Two years of preparation for pregnancy has not yet conceived consider infertility, need to consult a doctor in time to check the cause of the disease, may be female factors, male factors, male and female factors and so on. 1. Female factors: women have uterus, fallopian tube, ovary and other abnormalities, such as uterine malformation, tubalitis, tubal obstruction, luteal insufficiency, endometriosis, etc., resulting in sperm pathway abnormalities, ovulation abnormalities, etc., there is no way to form a fertilized egg. Or the endometrium is abnormal, the fertilized egg can not be normal bed. 2. Male factors: male semen abnormalities, there is no sperm or sperm count is too low, the vitality of the sperm is weakened, the morphology is abnormal. Men with impotence and premature ejaculation, etc., resulting in sperm can not enter the female vagina normally. 3. Both male and female factors: both men and women have sperm immunity, female body fluid immunity abnormalities, etc., leading to infertility. There are many possibilities for infertility, which need to be examined in the hospital to clarify the cause of the disease before targeted treatment.