The main manifestation of urine routine of kidney cancer is increased red blood cell count and hematuria, or there may be no abnormal manifestation. Urine routine of early stage kidney cancer can show normal, while hematuria can appear in advanced stage kidney cancer, especially when accompanied with renal pelvis invasion, hematuria is more common. Hematuria refers to the increase of red blood cells in urine, which can be divided into naked eye hematuria and microscopic hematuria. Microscopic hematuria is an average of more than 3 red blood cells per high power field of view on microscopic examination after centrifugal sedimentation of urine. Naked eye hematuria can be observed that the urine color is like soy sauce or wash water, and hematuria is also one of the triad signs of renal cancer. If early renal malignant tumor is confined within the kidney, most of them can be treated by radical surgery and hematuria can disappear. If tumor metastasis occurs, for metastatic renal cancer, it can be combined with targeted therapy and immunotherapy, etc. When kidney cancer appears, one should actively cooperate with doctors to improve the quality of life.