Waking up with tingling in the hands may be due to non-disease causes, such as improper sleeping position. It may also be caused by diseases, such as cervical spondylosis, carpal tunnel syndrome, ischemic cerebrovascular disease. 1. Improper sleeping position: If you sleep for a long time on one side of the hand or arm, it will cause blood circulation disorders, nerve compression, and the patient will have numbness in the hand after waking up. 2. Cervical spondylosis: when patients suffer from cervical spondylosis, cervical spine osteophytes, herniated discs will compress the nerves, coupled with improper sleeping posture or improper pillow, it may make the nerve compression more pronounced, resulting in numbness of the hands. 3. Carpal tunnel syndrome: this is a nerve compression disease. The patient’s involuntary movement of the hand during sleep at night may make the nerve compression more obvious, and the symptom of numbness of the hand will appear. 4. Ischemic cerebrovascular disease: patients with ischemic cerebrovascular disease have insufficient blood supply to the brain tissue, and the corresponding symptoms appear. The onset of the disease will involve the upper limbs, hands, lower limbs, often unilateral numbness, sensory impairment, dyskinesia. Numbness of the hands when waking up from sleep may also be caused by other diseases. When the patient often appears this symptom, it is recommended to go to the hospital as soon as possible, under the guidance of the doctor active treatment.