Itching in the urethra, possible causes: first, non-gonococcal urethritis, which is more common, seen in infection with mycoplasma and chlamydia. The source of infection is mostly spread through sexual contact, partners. The first symptom is itching in the urethra, accompanied by frequent urination, urinary urgency, painful urination and other discomforts. A thin discharge, often white, sometimes yellowish, is seen at the urethral orifice, and white or yellow scabs are seen on the underwear. It is recommended that the urethral discharge be retained for mycoplasma and chlamydia culture, and that urine be retained for mycoplasma and chlamydia culture. If the culture is positive, then the diagnosis can be confirmed, and need to carry out azithromycin intravenous infusion or roxithromycin for oral treatment. Secondly, acute bacterial urethritis, can also appear in the urethra itching symptoms, but often the urinary tract irritation symptoms are heavier, there is obvious urinary frequency, urinary urgency, urination pain. Usually there is no discharge, sometimes there can be yellow discharge. It is recommended that urine be retained for routine examination and bacterial culture examination, and if pathogenic bacteria are cultured, anti-infective treatment will be given.