There is no most effective way to get rid of age spots. Age spots, also known as seborrheic keratosis, can be triggered by age, hereditary factors, sun exposure, etc. The treatment options include medication, physical therapy, and surgery. In the treatment, one can choose medication, physical therapy and surgery. 1. Drug therapy: you can follow the doctor’s advice to choose the vitamin A acid that has the ability to regulate the abnormal differentiation of keratinocytes, which has been widely used in the treatment of many kinds of dermatological diseases at present. In addition, a 40% hydrogen peroxide solution can be applied to the skin surface. 2. Physical therapy: patients can choose cryotherapy and laser therapy under the guidance of the doctor, which can directly act on the melanin particles of the skin, and can lead to the destruction of melanocytes to achieve the purpose of treatment. 3. Surgical treatment: For single and large lesions of age spots, if the effect of physical treatment is not satisfactory, patients can choose surgical excision. The main choice is electrocautery, under local anesthesia, the hyperplastic tissues can be searched with low-voltage electric current, but it may leave scars. Elderly spots have no special impact on health and can usually be left untreated. If there is a need for treatment, it is recommended to go to a regular hospital, under the guidance of a professional doctor to choose the appropriate treatment, do not self-medication.